Search results for "radical reactions"

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Metal‐Free Electrochemical Synthesis of Sulfonamides Directly from (Hetero)arenes, SO2, and Amines

2021

Abstract Sulfonamides are among the most important chemical motifs in pharmaceuticals and agrochemicals. However, there is no methodology to directly introduce the sulfonamide group to a non‐prefunctionalized aromatic compound. Herein, we present the first dehydrogenative electrochemical sulfonamide synthesis protocol by exploiting the inherent reactivity of (hetero)arenes in a highly convergent reaction with SO2 and amines via amidosulfinate intermediate. The amidosulfinate serves a dual role as reactant and supporting electrolyte. Direct anodic oxidation of the aromatic compound triggers the reaction, followed by nucleophilic attack of the amidosulfinate. Boron‐doped diamond (BDD) electro…

chemistry.chemical_classificationGreen chemistryradical reactions010405 organic chemistrySupporting electrolytegreen chemistryoxidationCommunicationGeneral Chemistry010402 general chemistryElectrochemistry01 natural sciencesCombinatorial chemistryCatalysisCommunications0104 chemical sciencesSulfonamideSolventchemistryNucleophileElectrochemistry | Hot PaperelectrochemistrysulfonamidesElectrodeReactivity (chemistry)Angewandte Chemie (International Ed. in English)
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Electrochemical treatment of aqueous solutions containing one or many organic pollutants at boron doped diamond anodes. Theoretical modeling and expe…

2012

The electrochemical oxidation of organics in water at boron doped diamonds (BDD) was experimentally investigated with the aim to discuss the correlations among the conversion of the pollutants and the instantaneous current efficiency ICE with the operative conditions. A simple theoretical model previously developed for the oxidation of oxalic acid accounting for the cases of mass transfer control, oxidation reaction control and mixed kinetic regimes was adopted and extended to challenge its predictive capability in the case of organics of different nature and in systems with more pollutants. A quite good agreement, between theoretical predictions and experimental data pertaining to the elec…

General Chemical EngineeringRadicalChlorine compoundOxalic acidInorganic chemistryPollution Anodic oxidationElectrochemistryCarboxylic acidRedoxIndustrial and Manufacturing Engineeringchemistry.chemical_compoundElectron transferAOPs; BDD; Diamond anode; Oxygen evolution; Theoretical models Boron; Carboxylic acids; Chlorine compounds; Diamonds; Electrochemical oxidation; Electron transitions; Free radical reactions; Pollution Anodic oxidationMass transferDiamond anodeEnvironmental ChemistryAOPElectron transitionAqueous solutionOxygen evolutionGeneral ChemistrySettore ING-IND/27 - Chimica Industriale E TecnologicaFree radical reactionTheoretical models BoronElectrochemical oxidationchemistryDiamondBDDOxygen evolutionChemical Engineering Journal
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